| Rank | City | 1870 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Boston | 250,526 | 3.5% |
| 2 | Worcester | 41,105 | 5.1% |
| 3 | Lowell | 40,928 | 1.1% |
| 4 | Cambridge | 39,634 | 4.3% |
| 5 | Lawrence | 28,921 | 5.1% |
| 6 | Charlestown | 28,323 | 1.2% |
| 7 | Lynn | 28,233 | 4.0% |
| 8 | Fall River | 26,766 | 6.7% |
| 9 | Springfield | 26,703 | 5.8% |
| 10 | Salem | 24,117 | 0.8% |
| 11 | New Bedford | 21,320 | -0.4% |
| 12 | Taunton | 18,629 | 1.9% |
| 13 | Chelsea | 18,547 | 3.3% |
| 14 | Gloucester | 15,389 | 3.5% |
In 1870, the largest city in Massachusetts was Boston, with a population of 250,526. The second largest city is Worcester, with a population of 41,105.
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