| Rank | City | 1880 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Louisville | 123,758 | 2.1% |
| 2 | Covington | 29,720 | 1.9% |
| 3 | Newport | 20,433 | 3.1% |
In 1880, the largest city in Kentucky was Louisville/Jefferson County, with a population of 123,758. The second largest city is Covington, with a population of 29,720.
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