| Rank | City | 1880 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Detroit | 116,340 | 3.9% |
| 2 | Grand Rapids | 32,016 | 6.8% |
| 3 | Bay City | 20,693 | – |
In 1880, the largest city in Michigan was Detroit, with a population of 116,340. The second largest city is Grand Rapids, with a population of 32,016.
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